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Today's Top MLB Pitchers Strikeouts Prop Bets: 5 picks including Yoshinobu Yamamoto, Pablo Lopez and more for September 22nd, 2024

When an MLB starting pitcher takes the mound, they're likely to rack up a few strikeouts. It's arguably the best way to record an out, as it doesn't require any defense. Each pitcher is given an over/under line and it's up to sports bettors to make predictions based on that. To that end, we've compiled the best bets to look for today on DraftKings.


Best MLB strikeout prop bets for September 22

#5) Nick Pivetta: Under 6.5 -145

Take the under on Nick Pivetta today (Imagn)
Take the under on Nick Pivetta today (Imagn)

Nick Pivetta has been solid in the strikeout department for the Boston Red Sox, with a 29.6% K rate and 10.88 per nine innings. However, he has otherwise not pitched all that well, and he's up against the Minnesota Twins. They have a solid offense and are fighting for the playoffs, so take the under.


#4) Yoshinobu Yamamoto: Over 6.5 -145

Take the over on Yoshinobu Yamamoto (Imagn)
Take the over on Yoshinobu Yamamoto (Imagn)

Yoshinobu Yamamoto has pitched very well for the Los Angeles Dodgers when healthy, and that includes a 28.5% K rate and 10.43 per nine innings. Today, the Japanese star is taking on the lowly Colorado Rockies, so he's a safe bet to hit the over with ease.


#3) Pablo Lopez: Under 7.5 -160

Take the under on Pablo Lopez (Imagn)
Take the under on Pablo Lopez (Imagn)

Pablo Lopez has struck out 25.9% of the batters he has faced this year. He averages 9.58 per nine innings and has been very solid this year. However, his line is high and he has to take on the Boston Red Sox, so he's more likely to hit the under today.


#2) Paul Skenes: Over 6.5 -145 (Safest pick of the day)

Paul Skenes is today's safest prediction (Imagn)
Paul Skenes is today's safest prediction (Imagn)

Paul Skenes has been lights out in his rookie season, which is why he's the safest pick of the day. The Pittsburgh Pirates ace sports an otherworldly 32.2% K rate and 11.29 K/9. It doesn't matter very much who he faces, as he's likely to rack up the strikeouts with ease.


#1) Hunter Greene: Over 4.5 +105 (Bold Prediction of the day)

Hunter Greene is today's bold prediction (Imagn)
Hunter Greene is today's bold prediction (Imagn)

Hunter Greene has pitched very well for the Cincinnati Reds and boasts a solid 27.8% strikeout rate. Today, the ace is up against the Pittsburgh Pirates, who present a solid matchup. His line is pretty low, so despite the odds, he has a good chance of hitting the over.

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