Oregon vs. MI State football history: H2H, Records, and more ahead of Week 6 CFB Matchup

An exciting Big 10 rivalry matchup awaits in Week 6 as the Michigan State Spartans (3-2, 1-1 Big 10) hit the road to play against the No. 6 Oregon Ducks (4-0,1-0) in Autzen Stadium in Eugene. The game will kick off at 9 p.m. ET on Friday, Oct. 4, and fans can enjoy the live telecast on FOX Sports Networks.

This age-old rivalry returns after six years, so let's take a look at the Oregon vs. MI State head-to-head and other notable records to spice things up.

Oregon vs. MI State football Head-to-Head

NCAA Football: Redbox Bowl-Michigan State vs Oregon - Source: Imagn

Oregon and Michigan State played their first game on Sept. 15, 1979, at the Spartans' home turf in East Lansing. In that game, the Spartans had a decisive 41-17 victory over the Ducks. So far, these two teams have faced each other seven times, and currently, Oregon leads the head-to-head series 4-3.

Notable records in the Oregon vs. MI State Football Series

Here are some notable records in the Oregon vs. MI State rivalry:

Last five matchups - Oregon leads the last five matchups, winning three games, while Michigan State has won two.
Most Recent Game: In December 2018, Oregon defeated Michigan State 7-6, the lowest-scoring game in their rivalry. Oregon QB Justin Herbert, who now plays for the Los Angeles Chargers, threw a game-winning 28-yard touchdown to WR Dillon Mitchell.
Highest-Scoring Game: The highest-scoring game took place in September 2014, with Oregon winning 46-27.
Michigan State's Biggest Win: Michigan State's largest margin of victory was in 1979 when they won 41-17.
Oregon's Biggest Win: Oregon’s biggest victory was a 48-14 win.

Oregon Ducks overall records:

All-Time Record - 708-511-46
National Championships - 0
Conference Championships -13
Bowl Games - 37
Bowl Record - 17-20-0
Consensus All-American - 11
Heisman Winners - 1
NFL Draft Picks - 244
First Round NFL Draft Picks - 23

Michigan State Spartans overall records:

All-Time Record - 733-489-44
National Championships - 6
Conference Championships - 11
Bowl Games - 30
Bowl Record - 14-16-0
Consensus All-American - 33
Heisman Winners - 0
NFL Draft Picks - 323
First Round NFL Draft Picks - 36

Who is favored in Oregon vs. MI State?

The Oregon Ducks are heavily favored by 23.5 points against the Michigan State Spartans in Week 6. The money line is set at +1300 for Michigan State and -2800 for Oregon, with the over/under at 52.5.

The Ducks remain undefeated with four dominant wins. Last week, they beat the UCLA Bruins 34-13, which boosted their ranking from 8th to 6th. Meanwhile, the Spartans suffered their second straight loss of the season, falling 38-7 to the No. 3 Ohio State Buckeyes. With the Spartans as clear underdogs, can they pull off a stunning upset against the Ducks?