UFC 268: Usman vs. Covington is a mixed martial arts event produced by the Ultimate Fighting Championship that took place on November 6, 2021 at Madison Square Garden in New York, United States.
Main Card
| Weight Class | Fight | Method | Round | Results |
| Welterweight | Kamaru Usman vs. Colby Covington | Decision | R5 (05:00) | Kamaru Usman def. Colby Covington |
| Women's Strawweight | Rose Namajunas vs. Zhang Weili | Decision | R5 (05:00) | Rose Namajunas def. Zhang Weili |
| Bantamweight | Frankie Edgar vs. Marlon Vera | KO/TKO | R3 (03:50) | Marlon Vera def. Frankie Edgar |
| Featherweight | Shane Burgos vs. Billy Quarantillo | Decision | R3 (05:00) | Shane Burgos def. Billy Quarantillo |
| Lightweight | Justin Gaethje vs. Michael Chandler | Decision | R3 (05:00) | Justin Gaethje def. Michael Chandler |
Prelims Card
| Weight Class | Fight | Method | Decision | Round |
| Middleweight | Alex Pereira vs. Andreas Michailidis | KO/TKO | R2 (00:18) | Alex Pereira def. Andreas Michailidis |
| Lightweight | Al Iaquinta vs. Bobby Green | KO/TKO | R1 (02:25) | Bobby Green def. Al Iaquinta |
| Middleweight | Phil Hawes vs. Chris Curtis | KO/TKO | R1 (04:27) | Chris Curtis def. Phil Hawes |
| Middleweight | Edmen Shahbazyan vs. Nassourdine Imavov | KO/TKO | R2 (04:52) | Nassourdine Imavov def. Edmen Shahbazyan |
Early Prelims
| Weight Class | Fight | Method | Round | Results |
| Welterweight | Ian Garry vs. Jordan Williams | KO/TKO | R1 (04:59) | Ian Garry def. Jordan Williams |
| Heavyweight | Gian Villante vs. Chris Barnett | KO/TKO | R2 (02:23) | Chris Barnett def. Gian Villante |
| Light Heavyweight | Dustin Jacoby vs. John Allan | Decision | R3 (05:00) | Dustin Jacoby def. John Allan |
| Featherweight | Melsik Baghdasaryan vs. Bruno Souza | Decision | R3 (05:00) | Melsik Baghdasaryan def. Bruno Souza |
| Flyweight | CJ Vergara vs. Ode Osbourne | Decision | R3 (05:00) | Ode Osbourne def. CJ Vergara |
