5 NFL players who will miss Week 1 of 2022 season due to preseason injuries ft. Zach Wilson and Sam Darnold

Week 1 of the 2022 NFL season is just a couple of weeks away. All 32 teams are preparing their final game plans and finalizing their rosters. The preseason has concluded and the regular season is quickly approaching.

The NFL preseason and offseason programs offer teams an excellent opportunity at formally preparing for the upcoming season. But it also presents an additional risk of injury. Here are five players who are set to miss Week 1 of the 2022 NFL season due to injuries they suffered during the offseason.

#1 - Tyron Smith, Dallas Cowboys

Tyron Smith has spent all 12 seasons of his NFL career so far with the Dallas Cowboys. He has established himself as one of the best offensive tackles in the league. He's been selected to four All-Pro teams as well as going to eight Pro Bowls over the last nine years.

The Cowboys will need to prepare to be without their superstar offensive lineman after he suffered a devastating injury during the preseason. The severe leg injury includes a torn hamstring and an avulsion fracture in his knee. It's been reported that he will be out of action until at least December and could potentially miss the entire 2022 NFL season.

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#2 - Sam Darnold, Carolina Panthers

Sam Darnold has been locked in a quarterback battle with Baker Mayfield during the preseason. While Mayfield was eventually named the Carolina Panthers' starting quarterback for Week 1 and Darnold would serve as his backup.

The Panthers' depth at the quarterback position took a serious hit when Darnold went down with a high ankle sprain during their final preseason game. He is currently projected to miss the next first four to six weeks.