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Oklahoma Sooners vs Iowa State Cyclones Prediction, Odds, Line, Spread, and Picks - October 29 | 2022 NCAA Football Season

The Iowa State Cyclones (3-4) will host the Oklahoma Sooners (4-3) on Saturday (October 29) for a Big 12 conference matchup in the NCAA.

Iowa State is on a four-game losing streak and will be desperate to stop the bleeding. Meanwhile, Oklahoma snapped their three-game losing streak last week with a big conference win over No.19 Kansas 52-42.

The Cyclones will send every trick they have in the playbook to get a result this week, and that needs to play into betting on this game.

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Oklahoma Sooners vs Iowa State Cyclones Match Details

Fixture: Sooners @ Cyclones

Date and Time: Saturday, October 29; 12:00 pm EST

Venue: Jack Trice Stadium


Oklahoma Sooners vs Iowa State Cyclones Betting Odds

TeamSpreadMoneylineOver/Under
Oklahoma Sooners-1.5 (-110)-120Over 56.5 (-110)
Iowa State Cyclones+1.5 (-110)+100Under 56.5 (-110)

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Oklahoma Sooners vs Iowa State Cyclones Key Stats

The Iowa State Cyclones have lost their last four games all by less than one score. Their last three losses have been by a combined seven points total. Of all the Iowa State stats that could play a factor in this matchup, that may prove to be the most notable.

Iowa State averages 23 PPG while only allowing 15. The damaged but effective offense is good for 370 yards per game, but their coach mentioned having a fully healthy backfield this week for the first time.

The offense has been extremely pass focused; nearly 70% of plays have been passes, and that's due to RB bruises. Now that Brock and Norton are both fully operational, the Cyclones can enjoy playing against defenses that can't double down on the pass.

QB Hunter Dekkers has been solid even with that being the case; 1,850 yards and 13 touchdowns, but he has thrown seven interceptions. Look for the offense to be much more versatile and for Brock to open up the secondary for Dekkers.

The Oklahoma Sooners will face the Big 12's best defense this weekend. QB Dillon Gabriel will certainly be under rushing pressure and won't be taking his time to get the ball out.

Veteran RB Eric Gray has been massive for the Sooners this season with 700 yards and five touchdowns on 97 rushes. He's surely going to have a heavy workload in this must-win game, but he'll be running into a great defensive front. The Sooners averaged 34 points per game and 470+ yards. Expect these numbers to come down a bit, as Iowa State's defense could have its way.


Oklahoma Sooners vs Iowa State Cyclones Betting Prediction

Oklahoma should rise to the occasion against the best Big 12 defense and find the end zone a few times.

Iowa State's offense could open up new parts of the playbook and flex what a healthy unit looks like. Dekkers and the offense should come up clutch on late possessions and get the final punch. In a close, tight game the entire way, the Cyclones should take it. Go for the plus value.

Prediction: Iowa State Cyclones Moneyline (+100)

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